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Ing. Natallia Kulik, PhD.

Pozice

Vědecký asistent
Adresa
Zámek 136, CZ-373 33 Nové Hrady
kulik@nh.cas.cz

Dřívější výsledky

Education:
2000 - ­2005 – Belarussian National Technical University (Faculty of Natural Resources and Ecology),Minsk, Belarus, degree – Ing.
2006­ - 2011 – Doctoral study at the University of South Bohemia (Institute of Physical Biology), Nove Hrady, Czech Republic. Supervisor Prof. R. Ettrich. Ph.D in biophysics, thesis “Modeling substrate­ enzyme interactions in fungal hydrolases”

Employment:
2007 - 2011 - Researcher assistant, University of South Bohemia in Ceske Budejovice, Faculty of Sciences, Branisovska 31a, 370 05 Ceske Budejovice
2007 - 2011 - Research assistant, Institute of Nanobiology and Structural Biology, Academy of Sciences of the Czech Republic, Zamek 136, 373 33 Nove Hrady
2011 - ­2015 - junior researcher, Institute of Nanobiology and Structural Biology, Academy of Sciences of the Czech Republic, Zamek 136, 373 33 Nove Hrady
2016 - ­now - junior researcher, Institute of Microbiology, Academy of Sciences of the Czech Republic, Zamek 136, 373 33 Nove Hrady

Experience abroad:
2011 – 2 week stay in Princeton University in the J. Carey lab (USA), work on the project “Parameterization and docking of quinones with a long tail in the active site of WrbA”

Running research projects:
“Theoretical Study of Photosynthetic Processes in Photosystem II ” in association with D. Reha (Czech Republic, Nove Hrady) and M. Kuty (Czech Republic, Ceske Budejovice).

Activity in the field of study:
Theoretical study of protein structures, substrate/inhibitor – enzyme interaction, analysis of structure­ function relationship in a wide range of enzymes (hyrolases, nitrilases), stimulation of proteins in lipids. Parameterization of cofactors and lipids for Amber force field. Wide experience with homology modeling, phylogenetic analysis, molecular dynamics simulation of systems and molecular docking.

Ústavní publikace v impaktovaných časopisech